Université Paris Saclay / Université Paris Descartes
Régulation de la dynamique des microtubules et de leurs fonctions
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In our ongoing projects, we are using biochemistry, biophysics and structural biology in conjunction with cell and mouse biology to identify the molecular mechanisms by which tubulin posttranslational modifications regulative microtubule behaviour and functions, and which are the cellular and developmental roles of these modifications and the corresponding enzymes. Our functional studies are focussed on the nervous system, cilia and flagella (including spermatogenesis), and cell division.
Imagerie et Psychiatrie
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Cerebral development, imaging and psychopathology
The first axis of research is to characterize psychiatric disorders linked to brain development, using anatomical and functional neuroimaging. Patient groups with psychiatric disorders beginning in the early decades of life, are studied at complimentary periods: childhood, adolescence, adulthood.