glia in psychiatric and neurodegenerative diseasess

Groupe Interactions cellules gliales/cellules gliales et cellules gliales/neurones

Domaine de recherche principal: 

Neurophysiology / systems neuroscience

Mots clefs: 

synaptic transmission
plasticity
astrocytes
GPCR signaling
neuron-glia interactions in physiology of the central nervous system
neuron-astrocyte interactions
glia in memory and sleep
glia in psychiatric and neurodegenerative diseases

Labelisation ENP: 

2012

Centre de recherche / Institut: 

INCC - UMR 8002 - Paris Descartes University

Code unité de recherche: 

FR3636

We are interested in understanding the role of glial cells in the mammalian central nervous system (CNS) and the mechanisms by which glial cells and neurons interact to support normal communication in the CNS.

Leader

Leader: 

Établissements

Établissement de rattachement: 

CNRS

Établissements affiliés: 

Université Paris Descartes

Université: 

Université Paris Descartes

École doctorale: 

ED3C
Laboratory

Nom: 

UFR Biomédicale

Initiatives d'Excellence: 

Institut Neuroscience et Cognition
Publications

publications: 

Agulhon C, Sun MY, Murphy T, Myers T, Lauderdale K, Fiacco TA. Calcium signaling and gliotransmission in normal versus reactive astrocytes, Frontiers in Neuropharmacology. In Press.

Agulhon C, Fiacco TA, McCarthy KD , Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling, Science.327:1250-4, 2010.

Fiacco TA, Agulhon C, McCarthy KD. Sorting out astrocyte physiology from pharmacology, Annu Rev Pharmacol Toxicol. 49:151-174 2009.

Agulhon C, Petravicz J, McMullen AB, Sweger EJ, Minton SK, Taves SR, Casper KB, Fiacco TA, McCarthy KD. What is the role of astrocyte calcium in neurophysiology?, Neuron. 59:932-946, 2008.

Fiacco TA, Agulhon C, Taves S, Petravicz J, Casper K, Dong Xinzhong, Chen J, McCarthy KD. Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity, Neuron. 54:611-626, 2007.