Unraveling the transfer function of a cortical input layer
Dates:1 September 2016 - 31 December 2016
Date limite de candidature:1 September 2016
Lab rotation proposal: 3 months
~ Sep-Dec 2016 ~ Jan-March 2017 ~ Apr-June 2017
The billions of granule cells in the cerebellar cortex input layer are thought to implement optimal separation of the patterns of activity of its mossy fiber afferents. How separation is performed despite input correlations remains poorly understood. We combine in vivo optogenetic recordings of granule cells and local interneurons, in vitro optogenetic emulation of mossy fibers activity with ultrafast light-patterning devices and electrophysiological recordings to address this issue. These data are used to feed a theoretical framework of granular layer function.
Address: IBENS - Ecole Normale Supérieure - 46, rue d'Ulm 75005 Paris
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