A new method to analyze at unprecedented resolution the development of the Human Nervous System.
Dates:18 September 2017 - 29 June 2018
Date limite de candidature:29 June 2018
~ Sept-Dec 2017 (to be discussed)
~ Jan-March 2018
~ April-June 2018
Combining whole-mount immunocytochemistry with tissue-clearing and light-sheet microscopy 3D analysis of embryonic and fetal specimens, we now seek to decipher the mechanisms ruling the organization of the human nervous system and associated tissues; to reconstitute the embryonic landscape of axon guidance cues, and to enhance our understanding of neuronal fate allocation and brain patterning. This project is a decisive progress towards grasping the etiology of congenital neuropathies.
Reference: Belle, M., Godefroy D., Couly G., Malone, S.A., Collier F., Giacobini, P. and Chédotal A. (2017) Tridimensional visualization and analysis of early human development. Cell,169:161-173
Institut de la Vision - 17, rue Moreau 75012 Paris - +33 1 53 46 25 15 - firstname.lastname@example.org