Modeling the coexistence of different brain oscillations
Dates:1 September 2016 - 31 December 2016
Date limite de candidature:1 September 2016
Lab rotation proposal: 3 or 4 months
~ Sep-Dec 2016 ~ Jan-March 2017 ~ Apr-June 2017
The long-term goal of this project is to understand how and why the same types of oscillations are seen in the brain, as well as in different animals. Do they play a fundamental role in information processing ? We already have models (cortical or thalamo-cortical) for slow oscillation types such as delta and spindle oscillations. A short term project could be to identify elementary circuits that create a "resonance" at key frequencies (such as the "fast" gamma oscillations at 40 Hz for example). Then add this elementary circuit in network models, to see under which conditions the network could generate these oscillations, and possibly switch between oscillation types. The model could be directly compared to recordings made in human subjects during the wake-sleep cycle (work done in collaboration with the Human Brain Project and the European Institute of Theoretical Neuroscience in Paris).
This project is appropriate for a rotation, because there exists many proposed mechanisms to generate oscillations, for example based on excitatory-inhibitory loops, or loops between inhibitory cells, etc. So it is possible in a very short time to integrate such mechanisms into existing models. It could also be a start for a PhD project, possibly involving direct participation to experiments.
Address: UNIC, CNRS, 1 Avenue de la Terrasse, 91191 Gif sur Yvette; European Institute for Theoretical Neuroscience, Paris
Phone number: +33 1 69 82 34 35 ; Email: firstname.lastname@example.org