Equipe Audition

Domaine de recherche principal:

Neurophysiology / systems neuroscience

Description:

Mots clefs:

memory, learning, plasticity, human psychophysics, physiology in behaving ferrets

Labelisation ENP:

2017

Centre de recherche / Institut:

ENS Ecole Normale Supérieure

https://lsp.dec.ens.fr/fr/member/661/daniel-pressnitzer

Code unité de recherche:

UMR 8248

The Audition team is investigating the mechanisms of auditory perception, at the interface between low-level processing of acoustic features and high-level cognitive processes. We use a wide range of tools in order to address this research topic, from single unit recordings in behaving animals to advanced psychophysics and EEG in human subjects. Current projects in the lab revolve around three major threads:

Leader

Leader:

PRESSNITZER Daniel

Établissements

Établissement de rattachement:

CNRS

Établissements affiliés:

Ecole Normale Supérieure

Université:

Université Pierre et Marie Curie

École doctorale:

ED 3C - 158

Laboratory

Nom:

Laboratoire des Systèmes Perceptifs

Initiatives d'Excellence:

LabEx Institut d’Etude de la Cognition, IdEx Paris Sciences et Lettres

Publications

publications:

Agus, T.R., Thorpe, S.J., & Pressnitzer, D. (2010). Rapid formation of auditory memories: Insights from noise. Neuron. 66, 610-618.

Andrillon, T., Pressnitzer, D., Léger, D., & Kouider, S. (2017).Formation and suppression of acoustic memories in human sleep. NatureCommunications, 8: 179.

Boubenec Y, Lawlor J, Górska U, Shamma S & Englitz B (2017). Detecting changes in dynamic and complex acoustic scenes. eLife 2017;10.7554/eLife.24910.

Chambers, C., Akram, S. Adam, V., Pelofi, C., Sahani, M., Shamma, S., & Pressnitzer, D. (2017). Prior context in audition informs binding and shapes simple features. Nature Communications, 8:15027.

Andrillon, T., Kouider, S., Agus, T., & Pressnitzer, D. (2015).Perceptual learning of acoustic noise generates memory-evoked potentials. Current Biology, 25: 2823-2829.

Développement du cerveau

Domaine de recherche principal:

Neurogenetics / neurodevelopment

Description:

Mots clefs:

Brain Development, Neuronal networks, Genetic regulation, Drosophila, Mouse

Labelisation ENP:

2017

Centre de recherche / Institut:

Institut du Cerveau et de la Moelle épinière

http://icm-institute.org/fr/team/equipe-developpement-du-cerveau/

Code unité de recherche:

UMRS 1127 UMR 7225

Notre laboratoire s’intéresse au développement du cerveau et à sa capacité à se protéger des désordres mentaux, telles que la déficience intellectuelle et la neuro-dégénérescence. Bien que les medias, mais aussi la littérature scientifique, mettent l’accent sur la maladie du cerveau, il est bon de rappeler que la vaste majorité des gens – et d’animaux – sont en bonne santé et ne souffrent pas de désordres mentaux. En réalité, la robustesse du cerveau est telle que même des individus ayant subi des mutations qui pourraient conduire à un désordre mental ne développent aucun symptôme.

Leader

Leader:

HASSAN Bassem

Établissements

Établissement de rattachement:

Inserm

Établissements affiliés:

CNRS

Université Pierre et Marie Curie

École doctorale:

ED 3C - 158

Laboratory

Initiatives d'Excellence:

Allen Distinguished Investigator Award 2016

Publications

publications:

Weinberger, S., M. Topping, J. Yan, A. Claeys, N. De Geest, D. Ozbay, T. Hassan, X. He, J. T. Albert, B. A. Hassan^ and A. Ramaekers^. 2017. “Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function”. eLife pii: e26402.

Oliva C*, A. Soldano*, N. Mora, N. De Geest, A. Claeys, M-L Erfurth, J. Sierralta,, A. Ramaekers, D. Dascenco, R. Ejsmont, D. Schmucker, N. Sanchez-Soriano and B.A. Hassan. 2016. “Organization of Drosophila brain wiring by the mushroom body via a Slit-Robo-RPTP signaling complex”. Developmental Cell. 39:267-278.

Yuan L.*, S. Hu*, Z. Okray, X. Ren, N. De Geest, A. Claeys, J. Yan, E. Bellefroid, B.A. Hassan^ and X.J. Quan^. 2016. The Drosophila neurogenin Tap functionally interacts with the Wnt-PCP pathway to regulate neuronal extension and guidance. Development. 143:2760-6.

Quan, X-J, L. Yuan, L. Tiberi, A. Claeys, N. De Geest, J. Yan, W. R. Xie, T. J. Klisch, R. van der Kant, J. Shymkowitz, Frederic Rousseau, M. Bollen, M. Beullens, H. Y. Zoghbi, P. Vanderhaeghen, B. A. Hassan. 2016. “Post-translational control of the temporal dynamics of transcription factor activity regulates neurogenesis”. Cell 164:460-75.

Hassan, B. A. and P. Robin Hiesinger. 2015. "Beyond Molecular Codes: Simple Rules to Wire Complex Brains". Cell 163:285-91.

Functional imaging and behavior in zebrafish

Domaine de recherche principal:

Neurophysiology / systems neuroscience

Description:

Mots clefs:

light-sheet microscopy

neuroimaging

zebrafish

sensory-motor integration

circuit inference

Labelisation ENP:

2016

Centre de recherche / Institut:

Laboratoire Jean Perrin

http://www.labos.upmc.fr/ljp/?article6

Code unité de recherche:

UMR 8237

The overall objective of the group is to unravel principles of neural computations underlying sensory-motor integration in the vertebrate brain. We use the zebrafish larva as it currently constitutes the only vertebrate system amenable to whole-brain recording with cellular resolution. Using one- or two-photon light-sheet microscopy, we are able to monitor the long-term activity of the quasi-entirety of the 100,000 neurons that comprise the animal brain, as it performs basic sensory-motor tasks.

Leader

Leader:

DEBREGEAS Georges

Personnel

Membres de l'équipe:

Raphaël Candelier

Sergei Kruglik

Sébastien Wolf

Alexis Dubreuil

Sophia Karpenko

Guillaume Le Goc

Établissements

Établissement de rattachement:

UPMC

Établissements affiliés:

CNRS

Université:

Université Pierre et Marie Curie

École doctorale:

ED 564

Publications

publications:

Sensorimotor Computation underlying phototaxis in zebrafish. Sébastien Wolf, Alexis M. Dubreuil, Tommaso Bertoni, Urs Lucas Böhm, Volker Bormuth, Raphaël Candelier, Sophia Karpenko, David G. C. Hildebrand, Isaac H. Bianco, Rémi Monasson, Georges Debrégeas. Nature Communication, in press

Whole-brain functional imaging with two-photon light-sheet microscopy, S Wolf, W. Supatto, G. Debrégeas, P. Mahou, S. G Kruglik,J-M. Sintes, E. Beaurepaire, R. Candelier Nature Methods 12, 379–380 (2015)

An Amplitude Modulation/Demodulation Scheme for Whisker-Based Texture Perception, Y. Boubenec, L. N. Claverie, D. E. Shulz,G. Debrégeas, J. Neurosci. 34(33): 10832-10843 (2014)

Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy. T. Panier,S. Romano, R. Olive, T. Pietri, G. sumbre, R. Candelier, G. Debrégeas, Frontiers in Neural Circuits 7, 0065 (2013)

The role of fingerprints in the coding of tactile information probed with a biomimetic sensor, J. Scheibert, S. Leurent, A. Prevost et G. Debrégeas, Science 323 1503-1506 (2009). Reviewed in Science news, Science Update (radio), Science signaling, Nature news, Nature Research highlights, Nature Methods,Analytical Chemistry, Atten. Percept & Psych.

Signatures of granular microstructure in dense shear flows. D. Mueth, G. Debregeas, G. Karczmar, P. Eng, S. Nagel & H. Jaeger,Nature 406, 385-388 (2000)

FRONTlab: the frontal systems, functions and dysfunctions

Domaine de recherche principal:

Cognitive neurosciences / neuropsychology /neuroeconomy

Description:

Mots clefs:

cognition

behavior

executive functions

neuroimaging

Prefrontal cortex

Labelisation ENP:

2016

Centre de recherche / Institut:

Institut du Cerveau et de la Moelle épinière

http://icm-institute.org/fr/team/equipe-dubois-levy/

Code unité de recherche:

UMRS 1127 UMR 7225

The prefrontal cortex (PFC) is a major challenge in Neurosciences. This brain region controls behavior adaptation and highercognitive functions that are needed for complex social interaction, abstract thinking, reasoning, planning or creativity.

Leader

Leader:

LEVY Richard

Personnel

Membres de l'équipe:

Bruno DUBOIS Chef d'équipe

Antoni VALERO-CABRE

Benedicte BATRANCOURT

Emmanuelle VOLLE

Harald HAMPEL

Raffaella Lara MIGLIACCIO

Marc TEICHMAN

Michel THIEBAUT DE SCHOTTEN

Établissements

Établissement de rattachement:

Inserm

Établissements affiliés:

CNRS

UPMC

Publications

publications:

Azuar C, Reyes P, Slachevsky A, Volle E, Kinkingnehun S, Kouneiher F, Bravo E, Dubois B, Koechlin E, Levy R. Testing the model of caudo-rostral organization of cognitive control in the human with frontal lesions. Neuroimage. 2014 Jan 1;84:1053-60. doi: 10.1016/j.neuroimage.2013.09.031.

Aichelburg C, Urbanski M, Thiebaut de Schotten M, Humbert F, Levy R, Volle E. Morphometry of Left Frontal and Temporal Poles Predicts Analogical Reasoning Abilities. Cereb Cortex. 2014 Oct 19. pii: bhu254.

Lagarde J, Valabrègue R, Corvol JC, Garcin B, Volle E, Le Ber I, Vidailhet M, Dubois B, Levy R. Why do patients with neurodegenerative frontal syndrome fail to answer: ‘In what way are an orange and a banana alike?’. Brain. 2015 Feb;138(Pt 2):456-71. doi: 10.1093/brain/awu359.

Gil Gonen-Yaacovi Leonardo Cruz de Souza Richard Levy Marika Urbanski Goulven Josse Emmanuelle Volle. Rostral and caudal prefrontal contribution to creativity: A meta-analysis of functional imaging data. Front. Hum. Neurosci. Published on 14 Aug 2013, doi:10.3389/fnhum.2013.00465.

Thiebaut de Schotten M., Dell’Acqua F., Forkel S.J., Simmons A., Vergani F., Murphy D.G.M., Catani M. (2011) A lateralized brain network for visuospatial attentionNat Neurosci 14:1245-1246.(IF 14.191).

Multisensory signal processing: From whole-brain activity to behavior

Domaine de recherche principal:

Neurophysiology / systems neuroscience

Description:

Labelisation ENP:

2016

Centre de recherche / Institut:

Laboratoire Jean Perrin

http://www.labos.upmc.fr/ljp/?vbormuth

Code unité de recherche:

UMR 8237

Our brain needs to constantly fuse sensory information detected by our multiple senses in order to produce a seamless coherent representation of the world. Rather than being the exception, this binding process is ubiquitous to sensory-motor integration and is implicated in most cognitive functions. Its impairment is a cause of various pathologies, such as schizophrenia or autism. Multisensory processing operates on all brain levels from primary cortices over subcortical structures up to higher associative centers, while the smallest operational units are single multisensory neurons.

Leader

Leader:

BORMUTH Volker

Personnel

Membres de l'équipe:

Thomas Panier (PostDoc)

Kris Severi (PostDoc)

Geoffrey Migault (PhD)

Hugo Trentenseaux (PhD)

Matthieu Dujany (Master)

Louis Chevalier (Master)

Établissements

Établissement de rattachement:

Sorbonne Université

Établissements affiliés:

CNRS

Université:

UPMC

École doctorale:

ED 564

Publications

publications:

Bormuth, V., Barral, J., Joanny, J.F., Jülicher, F. & Martin, P. Transduction channels gating controls friction on vibrating hair-cell bundles in the ear.

PNAS 111, 7185-90 (2014)

Gardner, M.K.*, Zanic, M.*, Gell, C., Bormuth, V., & Howard J. Depolymerizing Kinesins Kip3 and MCAK Shape
Cellular Microtubule Architecture by Differential Control of Catastrophe.

CELL 147, 1092-1103 (2011)

Bormuth, V., Varga, V., Howard, J., & Schäffer, E. Protein friction limits diffusive and directed movements of kinesin motors on microtubules.

SCIENCE 325, 870 - 873 (2009)

Varga, V.*, Leduc, C.*, Bormuth, V., Diez, S., & Howard, J. inesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization.

CELL 138, 1174-83 (2009)

Bormuth, V.*, Otsu, Y.*, et al. Optical monitoring of neuronal activity at high frame rate with a digital random-access multiphoton (RAMP) microscope.

J. Neurosci. Methods 173(2), 259-270 (2008)

Contrôle Central du Comportement Alimentaire et de la Dépense Energétique (C3ADE)

Domaine de recherche principal:

Neurophysiology / systems neuroscience

Description:

Mots clefs:

food intake/obesity

métabolisme énergétique

Labelisation ENP:

2016

Centre de recherche / Institut:

Unité de Biologie Fonctionnelle et Adaptative BFA

http://bfa.univ-paris-diderot.fr/presentation-generale/

Code unité de recherche:

UMR 8251

Dans nos sociétés modernes, l’abondance de nourriture riche en énergie et le mode vie sédentaire entrainent un déséquilibre de la balance énergétique à l’origine du développement de l’obésité. Selon le World Health Organization (WHO), l’obésité au niveau mondial a plus que doublé depuis 1980. En 2008, 1,5 millions d’adultes de 20 ans et plus sont en surpoids. L’obésité est aussi considérée en France comme une épidémie.

Leader

Leader:

LUQUET Serge

Personnel

Membres de l'équipe:

Julien Castel

Raphaël Denis

Claire Martin

Mar Quiñones Téllez

Anne-Sophie Delbes

Chloé Berland

Olja Kacanski

Établissements

Établissement de rattachement:

Université Paris Diderot

Établissements affiliés:

CNRS

Université:

Université Paris Diderot

École doctorale:

ED157

Laboratory

Initiatives d'Excellence:

USPC, collaborative ANR 2016

Publications

publications:

Garcia-Caceres, C., Quarta, C., Gao, Y., Varela, L., Gruber T, Legutko, B., Jastroch M., Johansson, P., Ninkovic J, Yi, CX., Le Thuc O, Meyer, C., Pfluger, PT., Fernandez AM., Luquet, S., Woods SC., Torres-Alemán, I., Kahn, C.R., Götz, M., Horvath, TL. & Tschöp, MH*. (2016) Astrocytic insulin signaling couples brain glucose uptake with nutrient availability. Cell 166, 867-880. (IF 2015:32.857)

Denis, RG., Joly, A., Webber, E., Langlet, F., Schaeffer, M., Padilla, S., Cansell, C., Dehouck, B., Castel, J., Delbes, AS., Martinez, S.,Lacombe, A., Rouch, C., Kassis, N., Fehrentz,J-A., Martinez, J, Verdié, P., Hnasko, T, Palmiter, RD., Krashes, MJ., Güler, A., Magnan, C., Luquet, S (2015). Palatability can drive feeding independent of AgRP neurons. Cell Metab 22, 646-657. (IF 2015 :17.897)

Sun, X., Luquet, S., Small, DM. (2017). DRD2: Bridging the genome and ingestive behavior. Trends in Cognitive Sciences. Trends Cogn Sci 21, 372-384.. (IF 2015:17.85)

Geurts, L., Everard, A., Van Hul, M., Essaghir, A., Duparc, T., Matamoros, S., Plovier, H., Castel, J., Denis, R.G., Bergiers, M., Druart, C., Alhouayek, M., Delzenne, N.M., Muccioli, G.G., Demoulin, J.B., Luquet, S., and Cani, P.D. (2015). Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nature communications 6, 6495 (IF2015: 12.00)

Cansell, C., Castel, J., Denis, R., Rouch, C., Delbes, AS., Martinez, S., Mestivier, D., Finan, B., Maldonado-Aviles, J.G, Rijnsburger, M., Tschöp, M.H., DiLeone, R.J., Eckel, R.H., La Fleur, S., Magnan, C., Hnasko, T., Luquet., S (2014). Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding. Mol Psychiatry 19, 1095-1105. (IF2015: 13.314)

Brain Dynamics

Domaine de recherche principal:

Cognitive neurosciences / neuropsychology /neuroeconomy

Description:

Mots clefs:

Multisensory integration

magnetoencephalography

neural oscillations

temporal cognition

Labelisation ENP:

2016

Centre de recherche / Institut:

Neurospin

https://sites.google.com/site/virginievanwassenhove/research

Code unité de recherche:

U992

The Brain Dynamics group focuses on the chronoarchitecture of the Human brain supporting perception and cognition.Our work is committed to the view that perception and cognition rely on inferential brain processes which are fundamental to contemporary theories of cortical functions. Neural inferences are shaped by both hard and soft constraints e.g. cognitive architecture and plasticity, respectively.

Leader

Leader:

VAN WASSENHOVE Virginie

Établissements

Établissement de rattachement:

Inserm

Établissements affiliés:

CEA

Direction des Sciences du Vivant

Institut d'Imagerie BioMédicale

École doctorale:

ED158 3C

Laboratory

Nom:

Cognitive Neuroimaging Unit

Initiatives d'Excellence:

IDEX Neuro Saclay

Publications

publications:

Gauthier B, van Wassenhove V. Time Is Not Space: Core Computations and Domain-Specific Networks for Mental Travels. J Neurosci. 2016 Nov 23;36(47):11891-11903.

Martin, J. R., #Kösem, A., & #van Wassenhove, V. (2015). Hysteresis in Audiovisual Synchrony Perception. e0119365.

Strauss, M., Sitt, J. D., King, J. R., Elbaz, M., #Azizi, L., #Buiatti, M., ... & Dehaene, S. (2015). Disruption of hierarchical predictivecoding during sleep. Proceedings of the National Academy of Sciences, 112(11), E1353-E1362.

Strauss, M., Sitt, J., King, J. R., Elbaz, M., Azizi, L., #Buiatti, M., ... & Dehaene, S. (2015). Atteinte des processus de prédiction maisconservation de l’adaptation sensorielle au cours du sommeil. Médecine du Sommeil, 12(1), 58.

Strauss, M., Sitt, J., King, J. R., Elbaz, M., Naccache, L., #Van Wassenhove, V., & Dehaene, S. (2015). Atteinte des systèmesprédictifs dans le sommeil.Revue Neurologique, 171, A172.

#van Wassenhove, V., & #Grzeczkowski, L. (2015). Visual-induced expectations modulate auditory cortical responses. Frontiers inNeuroscience, 9, 11.

Physiologie et physiopathologie de la moelle épinière

Domaine de recherche principal:

Neurophysiology / systems neuroscience

Description:

Mots clefs:

ALS

electrophysiology in vivo and in vitro

spinal cord circuitry

motoneuron

Renshaw cell

Labelisation ENP:

2014

Centre de recherche / Institut:

INCC - UMR 8002 - Paris Descartes University

http://neurophys.biomedicale.parisdescartes.fr/fr/les-equipes/physiologie-et-phy...

Code unité de recherche:

UMR8119

Our team investigates the relationships between spinal motoneurons and the muscle fibers they are targeting, and how thisrelationship is altered in the context of a human degenerative disease of motoneurons (ALS). To do so, we have recently pioneeredtwo new preparations that allow studying the electrophysiological properties of identified spinal motoneurons.

Leader

Leader:

ZYTNICKI Daniel

Établissements

Établissement de rattachement:

CNRS

Établissements affiliés:

Université Paris Descartes

École doctorale:

ED3C

Publications

publications:

Leroy F, Lamotte d'Incamps B, Zytnicki D. Potassium currents dynamically set the recruitment and firing properties of F-type motoneurons in neonatal mice. J Neurophysiol. 2015 Sep;114(3):1963-73. doi: 10.1152/jn.00193.2015. Epub 2015 Aug 12.

Leroy F#, Lamotte d'Incamps B#, Imhoff-Manuel RD#, Zytnicki D#. (2014) Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis. Elife Oct14;3. doi: 10.7554/eLife.04046.

Lamotte d’Incamps B#, Ascher P. (2014) High affinity and low affinity heteromeric nicotinic acetylcholine receptors at central synapses. J Physiol. Oct 1;592(Pt 19):4131-6

Delestrée N#, Manuel M#, Iglesias C, Elbasiouny SM, Heckman CJ, Zytnicki D#. (2014) Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis. J. Physiol. Apr 1;592(Pt 7):1687-703

Ritter LK, Tresch MC, Heckman CJ, Manuel M#, Tysseling VM. (2014) Characterization of motor units in behaving adult mice shows a wide primary range. J Neurophysiol. Aug 1;112(3):543-51

Manuel M#, Zytnicki D#, Meunier C. (2014) The dendritic location of the L-type current and its deactivation by the somatic AHP current both contribute to firing bistability in motoneurons. Front Comput Neurosci. Jan 27;8:4.

Biomarqueurs prédictifs de la rechute et de la réponse dans les addictions et les troubles de l'humeur

Domaine de recherche principal:

Neurological and psychiatric diseases

Description:

Mots clefs:

addiction

Mood disorders

Neuropsychophamarcology

Genomics

Biomarkers

Labelisation ENP:

2015

Centre de recherche / Institut:

UMR-S 1144 Therapeutic Optimisation in Neuropsychopharmacology

http://www.umrs1144.com/43+equipe-1-biomarqueurs-de-la-rechute-et-de-la-reponse-...

Code unité de recherche:

UMRS 1144

La variabilité de la réponse de même que la prédiction de la rechute dans les pathologies récurrentes sont de vastes questions scientifiques. Cette variabilité de la réponse est particulièrement importante et imprévisible dans les addictions et dans les troubles de l’humeur rendant en grand partie compte des difficultés de prise en charge de ces pathologies. Pouvoir la prédire pour mieux la prévenir est un enjeu majeur pour le développement d'une médecine personnalisée.

Leader

Leader:

BELLIVIER Frank

Personnel

Membres de l'équipe:

Marie-Claire CYNTHIA

Jean-Louis LAPLANCHE

Jean-Pierre LEPINE

Emmanuel CURIS

Florence VORSPAN

Vanessa BLOCH

Frank QUESTEL

Sarah SPORTICHE

Gaël DUPUY

Établissements

Établissement de rattachement:

Inserm

Établissements affiliés:

Université Paris Descartes

Université Paris Diderot

École doctorale:

ED 436

Laboratory

Nom:

Variabilité de réponses aux psychotropes

Publications

publications:

Geoffroy PA# , Scott J, Boudebesse C, Lajnef M, Henry C, Leboyer M, Bellivier F# , Etain B. Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies. Acta Psychiatr Scand. 2014 28.

Geoffroy PA# , Bellivier F# , Scott J, Etain B. Seasonality and bipolar disorder: a systematic review, from admission rates to seasonality of symptoms. J Affect Disord. 2014 15;168:210-23.

Boudebesse C, Geoffroy PA# , Henry C, Germain A, Scott J, Lajnef M, Leboyer M, Bellivier F# , Etain B. Eur Psychiatry. 2014 4.

Geoffroy PA# , Boudebesse C, Bellivier F# , Lajnef M, Henry C, Leboyer M, Scott J, Etain B. Sleep in remitted bipolar disorder: a naturalistic case-control study using actigraphy. J Affect Disord. 2014 158:1-7.

Geoffroy PA# , Boudebesse C, Henrion A, Jamain S, Henry C, Leboyer M, Bellivier F# , Etain B. An ASMT variant associated with bipolar disorder influences sleep and circadian rhythms: a pilot study. Genes Brain Behav. 2014 13(3):299-304.

Développement et Evolution du Cerveau Antérieur (DECA)

Domaine de recherche principal:

Neurogenetics / neurodevelopment

Description:

Mots clefs:

Development, Evolution, Behavior, Adaptation, Evolutionary forces

Labelisation ENP:

2015

Centre de recherche / Institut:

Institut des Neurosciences Paris-Saclay NeuroPSI

http://neuro-psi.cnrs.fr/spip.php?article123

Code unité de recherche:

UMR9197

We address two questions:

1) Which mechanisms underly the evolution and the diversification of the vertebrate forebrain?

2) What are the evolutionary forces involved?

Leader

Leader:

RETAUX Sylvie

Établissements

Établissement de rattachement:

CNRS

Établissements affiliés:

Université Paris Sud

Université:

Université Paris Sud

École doctorale:

ED 568 BioSigNe

Laboratory

Nom:

Département Développement-Évolution

Initiatives d'Excellence:

Idex NeuroSaclay

Publications

publications:

Hinaux H, Devos L, Blin M, Elipot Y, Bibliowicz J, Alié A, Rétaux S. Sensory evolution in blind cavefish is driven by early embryonic events during gastrulation and neurulation. Development. 2016 Dec 1;143(23):4521-4532.

Yannick Elipot, Hélène Hinaux, Jacques Callebert, Jean-Marie Launay, Maryline Blin and Sylvie Rétaux (2014) A Mutation in theEnzyme Mono Amine Oxidase explains part of the Astyanax Cavefish Behavioural Syndrome. Nature Communications, 5:3647. IF10.

Yannick Elipot, Laurent Legendre, Stéphane Père, Frédéric Sohm and Sylvie Rétaux (2014) Astyanax transgenesis and husbandry:how cavefish enters the lab. Zebrafish, 11(4):291-9. IF3 (with cover picture)

Luis Espinasa, Jonathan Bibliowicz, William R. Jeffery, and Sylvie Rétaux. (2014) Enhanced prey capture skills in Astyanax cavefishlarvae are independent from eye loss. Evo Devo 5: 35.

Suzanne E. McGaugh, Joshua B. Gross, Bronwen Aken, Maryline Blin, Richard Borowsky, Domitille Chalopin, Hélène Hinaux, WilliamJeffery, Alex Keene, Li Ma, Pat Minx, Daniel Murphy, Kelly E. O’Quin, Sylvie Rétaux, Nicolas Rohner, Steve M. J. Searle, BethanyStahl, Cliff Tabin, Jean-Nicolas Volff, Masato Yoshizawa, Wes C. Warren. (2014) The cavefish genome reveals candidate genes foreye loss. Nature Communications, Oct 20; 5:5307.

Hélène Hinaux, Maryline Blin, Julien Fumey, Laurent Legendre, Didier Casane and Sylvie Rétaux (2014) Lens defects in Astyanaxmexicanus cavefish: focus on crystallin evolution and function. Developmental Neurobiology, 28. [Epub ahead of print].