Maria Magiera
Régulation de la dynamique des microtubules et de leurs fonctions
Domaine de recherche principal:
Neurogenetics / neurodevelopment
Mots clefs:
Neurodegeneration
tubulin code
microtubule cytoskeleton
posttranslational modifications
neuronal differentiation
Labelisation ENP:
2015
Centre de recherche / Institut:
Institut Curie - Centre de Recherche - Paris/Orsay
Code unité de recherche:
UMR3348
In our ongoing projects, we are using biochemistry, biophysics and structural biology in conjunction with cell and mouse biology to identify the molecular mechanisms by which tubulin posttranslational modifications regulative microtubule behaviour and functions, and which are the cellular and developmental roles of these modifications and the corresponding enzymes. Our functional studies are focussed on the nervous system, cilia and flagella (including spermatogenesis), and cell division.