Research Highlight: Imbalanced decision hierarchy in addicts now theorized

ENP team leader Boris Gutkin heads the Group for Neural Theory at the Εcole Normale Supérieure. He and Mehdi Keramati, recently honored with his doctoral degree, developed a theory that accounts for how illicit drugs hijack reward-related circuitry in the brain to create a conflict between what addicts "say they want to do" and what they actually do. This mathematical account of drug addiction highlights the complementary roles of the brain regions ventral striatum and dorsal striatum in the development of addiction.

For more details on their model, check out the article:

Keramati M, Gutkin B. Imbalanced decision hierarchy in addicts emerging from drug-hijacked dopamine spiraling circuit. PLoS One. 24 April 2013. 8(4):1-8. 

Figure 1. Hierarchical organization of behavior and the cortico-BG [basal ganglia] circuit.” From Keramati M, Gutkin B. PLoS One. 24 April 2013.

Check out Boris Gutkin's team webpage.