L'École des Neurosciences de Paris Île-de-France est une fondation créée en 2007 comme Réseau Thématique de Recherche Avancée (RTRA) sous l'impulsion du Ministère de la Recherche et de l'Enseignement Supérieur.
Le but de cette fondation de coopération scientifique est de promouvoir la recherche et faciliter ses applications avec un intérêt particulier porté à la formation, l’accueil et l’accompagnement scientifique.
ENP researcher Jean-François Brunet and his team published new findings on the evolutionary origin of somatic and visceral neurons (involved, respectively, in interactions with the outside world and in monitoring the interior milieu). He and his colleagues examined the somatic and visceral sensorimotor circuits in mollusks (gastropods and cephalopods), and observed that they expressed the same specific genes than in vertebrates.
The ENP team of Jocelyne Caboche and Peter Vanhoutte (UPMC) have pioneered findings on the interplay of two key neurotransmitter systems that are recruited by drugs of abuse to change behaviour, namely Dopamine and Glutamate. In this study, first-authored by ENP graduate alumni Emma Cahill, they asked whether direct receptor-receptor interactions could contribute to cocaine’s effects. This hypothesis was confirmed.
ENP team leader Hirac Gurden and his collaborators used a new ultrasound imaging technique and provided the first ever in vivo visualization of activity in the piriform cortex of rats during odor perception. This deep-seated brain structure plays an important role in olfaction, and was inaccessible to functional imaging until now.