ENP graduate student Shauna Katz contributed to a review on microRNA-9 (miR-9), a regulator of neurogenesis. Katz and her colleagues discussed the findings that miR-9 targets transcriptional regulators that are known to control progenitor state, even in adult neural stem cells. Some studies alternatively indicate that miR-9 has functions in differentiated neurons. MiR-9 has been linked to pathological states, though it is unclear if it serves to protect from neurodegeneration or if it contributes to disease progression. Get more information in the review:
Coolen M, Katz S, Bally-Cuif L. miR-9: a versatile regulator of neurogenesis. Front Cell Neurosci. 20 Nov 2013. 7:220.
Figure 1A from Coolen, Katz and Bally-Cuif. Front Cell Neurosci. 2013. The evolutionary history of the miR-9 family of genes.
Doctoral Fellowship (year 1-3) supported by la région IDF (DIM Cerveau et Pensée)