The general interest of the lab is to dissect the neuronal circuits implicated in reward learning and to understand how drugs co-opt these connections.
Goal directed actions, aimed to obtain a reward, motivate our behaviors and influence our decisions.
The goal of the GNT is to understand the basis of information processing in the brain by identifying links between collective neural dynamics and function.
Research in the team focuses on the cellular and molecular mechanisms of learning and memory and on identifying mechanisms responsible for memory dysfunction in brain pathologies. Our objective is to identify in different structures of the brain such as the hippocampus and cortex the cellular and molecular mechanisms underlying brain of plasticity, to characterize their role in the formation of memories and identify networks and brain structures within which these changes occur during the laying down of memories.
Our research is focused on encoding learning and memory in the basal ganglia, a set of subcortical nuclei implicated in the adaptive control of behavior. Reciprocally connected with the cerebral cortex and the limbic system, the basal ganglia participate to the detection of environmental cues and to the selection of appropriate actions based on motivation and expectancy of reward.