psychiatry

CELLULAR MECHANISMS OF NEUROTRANSMISSION

Main field of research: 

Neuropharmacology / cell signaling

Keywords: 

Depression
schizophrenia
psychiatry

ENP label: 

2014

Research Unit Code: 

UMR 894

Le projet de l'équipe est d’identifier de nouvelles protéines et de nouveaux mécanismes impliqués dans le trafic neuronal de récepteurs, dans le but de caractériser de nouvelles cibles thérapeutiques dans le domaine de la dépression, la schizophrénie et d’autres pathologies neuronales et psychiatriques.

Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

Université Paris Descartes

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED158
Publications

Publications: 

Al Awabdh Sana , ? Masson J., Hamon M., Emerit M.B., Darmon M. J Neurosci. 2012 32(41):14227-14241.

Sokoloff P, Leriche L, Diaz J, Louvel J, Pumain R. Naunyn Schmiedebergs Arch Pharmacol. 2013 Feb;386(2):107-24

M. Humbert-Claude, E. Davenas, F. Gbahou, L. Vincent and J. M. Arrang: Psychopharmacology (Berl). 2012;220(1):225-41.

F. Gbahou, A. Rouleau and J. M. Arrang: Br J Pharmacol. 2012 166(6):1860-71.

M. El Hage, J. Masson, A. Conjard-Duplany, B. Ferrier, G. Baverel and G. Martin: J Cereb Blood Flow Metab. 2012.

Social and Affective Neuroscience Team (SAN)

Main field of research: 

Cognitive neurosciences / neuropsychology /neuroeconomy

Keywords: 

Depression
psychiatry
MEG
emotion
perception
social processes
social and affective neuroscience
EEG
fMRI

ENP label: 

2014

Research Center / Institute: 

Institut du Cerveau et de la Moelle épinière

Research Unit Code: 

UMRS 1127 UMR 7225

The SAN team gathers together three PIs with complementary expertise in affective neuroscience, social neuroscience, and psychiatry. Our project focuses on the functional neuroanatomy of the emotional brain. We study the brain systems of emotion detection, evaluation, and regulation, with an emphasis on how social processes (eg social inclusion) activate and regulate the emotional brain. Dysfunction of the emotional brain is central to many mental disorders and in particular to major depressive disorder (MDD).

Leader

Leader: 

Personal

Team members: 

MILLET Bruno
Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CNRS
Université Pierre et Marie Curie

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED 158
Laboratory

Initiatives d'Excellence: 

Institute for Translational Neuroscience (IHU-A-ICM), Paris
Publications

Publications: 

Mauras, T., Masson, M., Fossati, P*., & Pessiglione, M*. (2016). Incentive Sensitivity as a Behavioral Marker of Clinical Remission From Major Depressive Episode. Journal of Clinical Psychiatry, 77(6), E697-+. * equal contribution

Rotge, J. Y., Poitou, C., Fossati, P., Aron-Wisnewsky, J., & Oppert, J. M. (2017). Decision-making in obesity without eating disorders: a systematic review and meta-analysis of Iowa gambling task performances. Obes Rev.

Resibois, M., Verduyn, P., Delaveau, P., Rotge, J. Y., Kuppens, P., Van Mechelen, I., & Fossati, P. (2017). The neural basis of emotions varies over time: Different regions go with onset- and offset-bound processes underlying emotion intensity. Soc Cogn Affect Neurosci. doi: 10.1093/scan/nsx051. [Epub ahead of print]

Delaveau, P., Arruda Sanchez, T., Steffen, R., Deschet, K., Jabourian, M., Perlbarg, V., Gasparetto, E. L., Dubal, S., Costa, E. S. J., & Fossati, P. (2017). Default mode and task-positive networks connectivity during the N-Back task in remitted depressed patients with or without emotional residual symptoms. Hum Brain Mapp.

Burra, N., Baker, S., & George, N. (2017). Processing of gaze direction within the N170 / M170 time window: A combined EEG / MEG study. Neuropsychologia.

 

Behavior, Emotion and Basal Ganglia

Main field of research: 

Neurological and psychiatric diseases

Keywords: 

Parkinson
Tourette
basal
ganglia
Depression
psychiatry
Experimental Psychology
refractory disease
OCD
translational medicine

ENP label: 

2007

Research Center / Institute: 

Institut du Cerveau et de la Moelle épinière

Research Unit Code: 

UMRS 1127 UMR 7225

The scientific core of our research program is to study the exact nature of the processing that the basal ganglia (BG) apply to cortical information with three perspectives: 1) improve our fundamental knowledge of the cerebral mechanisms of information processing; 2) better understand the pathophysiology of human diseases which are related to BG dysfunction; and 3) develop innovative treatments for neuropsychiatric refractory disorders notably by means of the deep brain stimulation (DBS) functional neurosurgery.

Leader

Leader: 

Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CNRS
Université Pierre et Marie Curie

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED158
Laboratory

Surname: 

SERBERA Marie-Catherine

Initiatives d'Excellence: 

IHU ICM
Publications

Publications: 

Morgiève M#, N'Diaye K#, Haynes WI#, Granger B, Clair AH#, Pelissolo A, Mallet L#. Dynamics of psychotherapy-related cerebral haemodynamic changes in obsessive compulsive disorder using a personalized exposure task in functional magnetic resonance imaging. Psychol Med. 2014 May;44(7):1461-73.

Burbaud P#, Clair AH#, Langbour N, Fernandez-Vidal S#, Goillandeau M, Michelet T, Bardinet E#, Chéreau I, Durif F, Polosan M, Chabardès S, Fontaine D, Magnié-Mauro MN, Houeto JL, Bataille B, Millet B, Vérin M, Baup N, Krebs MO, Cornu P, Pelissolo A, Arbus C, Simonetta-Moreau M, Yelnik J#, Welter ML, Mallet L#. Neuronal activity correlated with checking behaviour in thesubthalamic nucleus of OCD patients. Brain, 2013 Jan;136(Pt 1):304-17

Clair AH#, N'Diaye K#, Baroukh T, Pochon JB, Morgieve M#, Hantouche E, Falissard B, Pelissolo A, Mallet L#. Excessive checking for non-anxiogenic stimuli in obsessive-compulsive disorder. Eur Psychiatry 2012. 10.1016

Buot A#, Welter ML, Karachi C, Pochon JB, Bardinet E#, Yelnik J#, Mallet L#. Processing of emotional information in the human subthalamic nucleus. J Neurol Neurosurg Psychiatry 2012. 10.1136/jnnp-2011-302158

Palminteri S, Clair AH#, Mallet L#, Pessiglione M. Similar improvement of reward and punishment learning by serotonin reuptakeinhibitors in obsessive-compulsive disorder. Biol Psychiatry 2012; 72: 244-250.