Neurophysiology

Brain Rhythms and Neural Coding of Memory

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

Neurophysiology
Neuromodulation
neural oscillation
decision
visual handicap

ENP label: 

2014

Research Center / Institute: 

Collège de France

Research Unit Code: 

UMR7241 - U1050

Our research targets the neurophysiological basis of spatial navigation and memory, in particular the network processes that integrate internal signals (representations, expectations, emotions) and multisensory information from the environment to store and update memories, and guide behavior. We record large neuronal ensembles and local field potential oscillations in freely moving animals performing learning and memory tasks. We focus on the hippocampal system (affected in epilepsy and Alzheimer's disease), where neurons code for the position and direction of the head in space.

Leader

Leader: 

Personal

ENP Students: 

Team members: 

Sidney WIENER
Susan SARA
Chantal MILLERET
Institutions

Principal Institution: 

Collège de France

Affiliated institutions: 

CNRS
Inserm

Doctoral School: 

ED 158 - 474
Laboratory

Surname: 

Center for Interdisciplinary Research in Biology (CIRB)

Initiatives d'Excellence: 

LabEx Memolife - ANR 2017
Publications

Publications: 

Maingret N, Girardeau G, Todorova R, Goutierre M1,2,3,4, Zugaro M. Hippocampo-cortical coupling mediates memory consolidation during sleep. Nat Neurosci. 2016 Jul;19(7):959-64. doi: 10.1038/nn.4304. Epub 2016 May 16.

Catanese J, Viggiano A, Cerasti E, Zugaro MB, Wiener SI. (2014) Retrospectively and prospectively modulated hippocampal place responses are differentially distributed along a common path in a continuous T-maze. J Neurosci. 34(39):13163-9

Cei A, Girardeau G, Drieu C, Kanbi KE, Zugaro M. Reversed theta sequences of hippocampal cell assemblies during backward travel. Nat Neurosci. 2014 May;17(5):719-24.

Girardeau G, Cei A, Zugaro M. Learning-induced plasticity regulates hippocampal sharp wave-ripple drive. J Neurosci. 2014 Apr 9;34(15):5176-83.

Arleo A, Déjean C, Allegraud P, Khamassi M, Zugaro M, Wiener SI (2013) Optic flow stimuli update anterodorsal thalamus head direction neuronal activity in rats. J. Neuroscience 33(42):16790-5.

Catanese J, Cerasti E, Zugaro M, Viggiano A, Wiener S.I.(2012) Dynamics of decision-related activity in prospective hippocampal place cells. Hippocampus 22(9):1901-11 

CENIR NeuroImaging

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

MEG
EEG
IRM
Neurophysiology
Cognitive science
Pathologies cérébrales
Pathologies médullaires

ENP label: 

2007

Research Center / Institute: 

Institut du Cerveau et de la Moelle épinière

Research Unit Code: 

UMRS 1127 UMR 7225

Le CENIR a pu commencer ses activités de recherche en neuro-imagerie grâce à la coopération financière de grandes institutions publiques et de prestigieux partenaires privés. L'ENP a cofinancé l'antenne tête 32 canaux et 100% de leur système EEG. 

Leader

Leader: 

Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CNRS
Université Pierre et Marie Curie

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED158
Laboratory

Initiatives d'Excellence: 

IHU-A-ICM, FLI, Neuratris
Publications

Publications: 

Gargouri F, Messé A, Perlbarg V, Valabregue R, McColgan P, Yahia-Cherif L, Fernandez-Vidal S, Ben Hamida A, Benali H, Tabrizi S, Durr A, Lehéricy S. Longitudinal changes in functional connectivity of cortico-basal ganglia networks in manifests and premanifest huntington's disease. Hum Brain Mapp. 2016 Jul 12. doi: 10.1002/hbm.23299. 

Rosso C, Valabregue R, Arbizu C, Ferrieux S, Vargas P, Humbert F, Attal Y, Messé A, Zavanone C, Meunier S, Cohen L, Delmaire C, Thielscher A, Herz DM, Siebner HR, Samson Y, Lehéricy S. The eye of the self: precuneus volume and visual perspective during autobiographical memory retrieval. Brain Struct Funct. 2014 May;219(3):959-68. doi: 10.1007/s00429-013-0546-2. Epub 2013 Apr 4.

Fasoula A, et al. Comparative performance evaluation of data-driven causality measures applied to brain networks. J Neurosci Methods (2013), http://dx.doi.org/10.1016/j.jneumeth.2013.02.021

Attal Y, Schwartz D Assessment of Subcortical Source Localization Using Deep Brain Activity Imaging Model with Minimum Norm Operators: A MEG Study. PLoS ONE (2013) 8(3): e59856. doi:10.1371/journal.pone.0059856

Dalal, SS., Jerbi, K., Bertrand, O., Adam, C., Ducorps, A., Schwartz, D., Garnero, L., Baillet, S., Martinerie, J., Lachaux, J-P. Evidence for MEG detection of hippocampus oscillations and cortical gamma-band activity from simultaneous intracranial EEG. Epilepsy & Behavior (2013) 28 (2), 310-311. Dio: 10.1016/j.yebeh.2012.04.032

Ulloa, J.L., Puce, A., Hugueville, L., & George, N. (2013). Sustained neural activity to gaze and emotion perception in dynamic social scenes. SCAN, in press. doi: 10.1093/scan/nss141

Dumas, T., Dubal, S., Attal, Y., Morel, S., Chupin, M., Jouvent, R., & George, N. (2013). MEG evidence for early amygdala responses to fearful faces in healthy adults. PloS ONE, 8(9): e74145. oi:10.1371/journal.pone.0074145.