François ROUYER
Research Director
ED 419 ED 426


Our group works on the circadian clock that controls the rest-activity rhythms in the drosophila brain. We have three main research lines:- Neuronal bases of the brain clock: role of the different...



Research director at INSERM and group leader (Molecular genetics of circadian rhythms) at Institut de Neurobiologie Alfred Fessard, Gif-sur-Yvette, Francois Rouyer's fields of expertise are neurogenetics, circadian clock, sleep-wake cycles, photoreception and drosophila. He teaches at Université Paris-Sud, Orsay and École Normale Supérieure, Paris. François Rouyer is deputy director of the Neurobiology & Development unit (CNRS UPR 3294) at INAF, is team leader at FRM (2018) and is a member of the scientific advisory board of the École Doctorale “Genes, genomes, cells” of  Paris-Sud University. 

 A selection of recent publications  

Chatterjee, A., Lamaze, A., De, J., Mena, W., Chélot, E., Martin, B., Hardin, P., Kadener, S., Emery, P., and Rouyer, F. (2018). Reconfiguration of a multi-oscillator network by light in the Drosophila circadian clock. Curr Biol (epub) 

Szabó, Á., Papin, C., Cornu, D., Chélot, E., Lipinszki, Z., Udvardy, A., Redeker, V., Mayor, U., and Rouyer, F. (2018). Ubiquitylation Dynamics of the Clock Cell Proteome and TIMELESS during a Circadian Cycle. Cell Rep 23, 2273-2282.

Arganda-Carreras, I., Manoliu, T., Mazuras, N., Schulze, F., Iglesias, J. E., Bühler, K., Jenett, A., Rouyer, F., and Andrey, P. (2018). A Statistically Representative Atlas for Mapping Neuronal Circuits in the Drosophila Adult Brain. Front Neuroinform 12, 13.

Saint-Charles, A., Michard-Vanhée, C., Alejevski, F., Chélot, E., Boivin, A., and Rouyer, F. (2016). Four of the six Drosophila rhodopsin-expressing photoreceptors can mediate circadian entrainment in low light. J Comp Neurol 524, 2828-2844.

Andreazza, S., Bouleau, S., Martin, B., Lamouroux, A., Ponien, P., Papin, C., Chélot, E., Jacquet, E., and Rouyer, F. (2015). Daytime CLOCK Dephosphorylation Is Controlled by STRIPAK Complexes in Drosophila. Cell Rep 11, 1266-1279.