Gabaergic synapses in the cerebellum
Research center
Institution
Laboratory
Keywords
Publications
Miki T, Malagon G, Pulido C, Llano I, Neher E, Marty A. Actin- and Myosin-Dependent Vesicle Loading of Presynaptic Docking Sites Prior to Exocytosis. Neuron. 2016 Aug 17;91(4):808-23. doi: 10.1016/j.neuron.2016.07.033.
Pulido C, Trigo FF, Llano I, Marty A. Vesicular release statistics and unitary postsynaptic current at single GABAergic synapses. Neuron. 2015 Jan 7;85(1):159-72. doi: 10.1016/j.neuron.2014.12.006. Epub 2014 Dec 24.
Alcami P, Marty A. Estimating functional connectivity in an electrically coupled interneuron network. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4798-807. doi: 10.1073/pnas.1310983110. Epub 2013 Nov 18.
Lamotte d'Incamps B, Krejci E, Ascher P (2012) Mechanisms shaping the slow nicotinic synaptic current at the motoneuron-renshaw cell synapse. J. Neurosci 32:8413-8423
Mejia-Gervacio, S. V. (2012). Muscarinic control of AMPA receptor responsiveness in mouse spinal cord motoneurons. J. Physiol. in press.
Palma-Cerda F, Auger C, Crawford DJ, Hodgson ACC, Reynolds SJ, Cowell JK, Swift KAD, Cais O, Vyklicky L, Corrie JET, Ogden D (2012) New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology 63:624-634
Pessac B, Nimmagadda VK, Makar T, Fishman PS, Bever CT, Trisler D (2012) Adult hematopoietic progenitors are multipotent in chimeric mice. C. R. Biol 335:454-462
Rossi B, Ogden D, Llano I, Tan YP, Marty A, Collin T (2012) Current and Calcium Responses to Local Activation of Axonal NMDA Receptors in Developing Cerebellar Molecular Layer Interneurons. PLoS One 7 7(6): e39983
Fields of research
Research Theme
This team employs a multidisciplinary approach including physical methods (optics), mathematical methods (statistical treatment of data and modelling) as well as chemical methods (synthesis of new compounds). It develops new techniques to study intercellular communication in the brain tissue. Currents lines of research concern the role of internal calcium stores in pre- and postsynaptic signalling; the functional implication of endogenous calcium buffers in presynaptic calcium signalling; the role of ionotropic presynaptic receptors in the regulation of the firing pattern and of the release probability.