Brain Rhythms and Neural Coding of Memory


Research center

11 place Marcelin Berthelot
75231 Paris
Thomas Römer


Collège de France
ED 158 - 474


Center for Interdisciplinary Research in Biology (CIRB)
UMR7241 - U1050
LabEx Memolife - ANR 2017


neural oscillation
visual handicap


Maingret N, Girardeau G, Todorova R, Goutierre M1,2,3,4, Zugaro M. Hippocampo-cortical coupling mediates memory consolidation during sleep. Nat Neurosci. 2016 Jul;19(7):959-64. doi: 10.1038/nn.4304. Epub 2016 May 16.

Catanese J, Viggiano A, Cerasti E, Zugaro MB, Wiener SI. (2014) Retrospectively and prospectively modulated hippocampal place responses are differentially distributed along a common path in a continuous T-maze. J Neurosci. 34(39):13163-9

Cei A, Girardeau G, Drieu C, Kanbi KE, Zugaro M. Reversed theta sequences of hippocampal cell assemblies during backward travel. Nat Neurosci. 2014 May;17(5):719-24.

Girardeau G, Cei A, Zugaro M. Learning-induced plasticity regulates hippocampal sharp wave-ripple drive. J Neurosci. 2014 Apr 9;34(15):5176-83.

Arleo A, Déjean C, Allegraud P, Khamassi M, Zugaro M, Wiener SI (2013) Optic flow stimuli update anterodorsal thalamus head direction neuronal activity in rats. J. Neuroscience 33(42):16790-5.

Catanese J, Cerasti E, Zugaro M, Viggiano A, Wiener S.I.(2012) Dynamics of decision-related activity in prospective hippocampal place cells. Hippocampus 22(9):1901-11 

Fields of research

Neurophysiology / systems neuroscience

Research Theme

Our research targets the neurophysiological basis of spatial navigation and memory, in particular the network processes that integrate internal signals (representations, expectations, emotions) and multisensory information from the environment to store and update memories, and guide behavior. We record large neuronal ensembles and local field potential oscillations in freely moving animals performing learning and memory tasks. We focus on the hippocampal system (affected in epilepsy and Alzheimer's disease), where neurons code for the position and direction of the head in space. To understand how this activity is implicated in memorization and in informing ongoing behavior, we simultaneously record in downstream structures such as prefrontal cortex (affected in schizophrenia) and ventral striatum (affected in Parkinson's disease). This provides tractable experimental models for high-level cognitive representations at the level of single neurons and neural networks.

ENP Students


Team members

Susan SARA