Functional role of the ferret prefrontal cortex in attention-demanding auditory tasks
Dates:January 2, 2018 - June 29, 2018
Application deadline:June 29, 2018
~ Jan-March 2018
~ April-June 2018
In this project, we propose to test the two following hypothesis:(i) Does the prefrontal cortex (PFC) have a causal impact on animal performance of attention-demanding auditory tasks, just as it has been shown in the visual domain?(ii) Does the role of prefrontal cortex change with increasing task difficulty, given that attentional effects on behavior and neural activity are strongest in challenging task conditions?To address these research questions, we will inactivate the PFC of trained ferrets during behavior on auditory tasks. This will enable us to determine whether ferrets are in any way reliant for PFC activity in order to succeed in the task. Concurrent electrophysiological recordings will be performed to confirm the PFC inactivation and its effect on auditory cortex.
Ecole Normale Supérieure - Laboratoire des Systèmes Perceptifs - 29, rue d’Ulm 75005 Paris - +33 1 44 32 26 78 - firstname.lastname@example.org