Neurophysiology / systems neuroscience

Audition Team

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

memory, learning, plasticity, human psychophysics, physiology in behaving ferrets

ENP label: 

2017

Research Center / Institute: 

ENS Ecole Normale Supérieure

Research Unit Code: 

UMR 8248

The Audition team is investigating the mechanisms of auditory perception, at the interface between low-level processing of acoustic features and high-level cognitive processes. We use a wide range of tools in order to address this research topic, from single unit recordings in behaving animals to advanced psychophysics and EEG in human subjects. Current projects in the lab revolve around three major threads:

Leader

Leader: 

Institutions

Principal Institution: 

CNRS

Affiliated institutions: 

Ecole Normale Supérieure

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED 3C - 158
Laboratory

Surname: 

Laboratoire des Systèmes Perceptifs

Initiatives d'Excellence: 

LabEx Institut d’Etude de la Cognition, IdEx Paris Sciences et Lettres
Publications

Publications: 

Agus, T.R., Thorpe, S.J., & Pressnitzer, D. (2010). Rapid formation of auditory memories: Insights from noise. Neuron. 66, 610-618.

Andrillon, T., Pressnitzer, D., Léger, D., & Kouider, S. (2017).Formation and suppression of acoustic memories in human sleep. NatureCommunications, 8: 179.

Boubenec Y, Lawlor J, Górska U, Shamma S & Englitz B (2017). Detecting changes in dynamic and complex acoustic scenes. eLife 2017;10.7554/eLife.24910.

Chambers, C., Akram, S. Adam, V., Pelofi, C., Sahani, M., Shamma, S., & Pressnitzer, D. (2017). Prior context in audition informs binding and shapes simple features. Nature Communications, 8:15027.

Andrillon, T., Kouider, S., Agus, T., & Pressnitzer, D. (2015).Perceptual learning of acoustic noise generates memory-evoked potentials. Current Biology, 25: 2823-2829.

 

Brain Development Team

Main field of research: 

Neurogenetics / neurodevelopment

Keywords: 

Brain Development, Neuronal networks, Genetic regulation, Drosophila, Mouse

ENP label: 

2017

Research Center / Institute: 

Institut du Cerveau et de la Moelle épinière

Research Unit Code: 

UMRS 1127 UMR 7225

Our lab is interested in how a brain develops and how it is protected from disorders, like intellectual disability and neurodegeneration.Although the emphasis in the media and, even the scientific literature tends to be on brain disease, it is worth remembering that vastmajority of people - and indeed animals - are in fact healthy and do not suffer from brain disorders. In fact, brain health is so robustthat often even individuals with mutations that could lead to disease do not develop the symptoms. How does brain developmentresist dysregulation more than 95% of the time?

Leader

Leader: 

Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CNRS
Université Pierre et Marie Curie

Doctoral School: 

ED 3C - 158
Laboratory

Initiatives d'Excellence: 

Allen Distinguished Investigator Award 2016
Publications

Publications: 

Hassan, B. A. and P. Robin Hiesinger. 2015. Beyond Molecular Codes: Simple Rules to Wire Complex Brains. Cell 163:285-91.

Okray, Z., C E.F. de Esch, H. Van Esch, K. Devriendt, A. Claeys, J. Yan, J. Verbeeck, G. Froyen, R. Willemsen, F. M.S. de Vrij, and B. A. Hassan. 2015. A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function. EMBO Mol. Med. 7:423-37.

Langen M., M. Koch, J. Yan, N. De Geest, M-L Erfurth, B. D. Pfeiffer, D. Schmucker, Y. Moreau and B. A. Hassan. 2013. Mutual inhibition among neighboring postmitotic neurons regulates individuality and robustness of brain wiring. eLife 2:e00337.

Xiao-Jiang Quan, Liqun Yuan, Luca Tiberi, Annelies Claeys, Natalie De Geest, Jiekun Yan, Rob van der Kant, Wei R. Xie, Tiemo J. Klisch, Joost Shymkowitz, Frederic Rousseau, Mathieu Bollen, Monique Beullens, Huda Y. Zoghbi, Pierre Vanderhaeghen, Bassem A. Hassan. Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis.

FRONTlab: the frontal systems, functions and dysfunctions

Main field of research: 

Cognitive neurosciences / neuropsychology /neuroeconomy

Keywords: 

cognition
behavior
executive functions
neuroimaging
Prefrontal cortex

ENP label: 

2016

Research Center / Institute: 

Institut du Cerveau et de la Moelle épinière

Research Unit Code: 

UMRS 1127 UMR 7225

The prefrontal cortex (PFC) is a major challenge in Neurosciences. This brain region controls behavior adaptation and highercognitive functions that are needed for complex social interaction, abstract thinking, reasoning, planning or creativity.

Leader

Leader: 

Personal

Team members: 

Bruno DUBOIS Chef d'équipe
Antoni VALERO-CABRE
Benedicte BATRANCOURT
Emmanuelle VOLLE
Harald HAMPEL
Raffaella Lara MIGLIACCIO
Marc TEICHMAN
Michel THIEBAUT DE SCHOTTEN
Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CNRS
UPMC
Publications

Publications: 

Azuar C, Reyes P, Slachevsky A, Volle E, Kinkingnehun S, Kouneiher F, Bravo E, Dubois B, Koechlin E, Levy R. Testing the model of caudo-rostral organization of cognitive control in the human with frontal lesions. Neuroimage. 2014 Jan 1;84:1053-60. doi: 10.1016/j.neuroimage.2013.09.031.

Aichelburg C, Urbanski M, Thiebaut de Schotten M, Humbert F, Levy R, Volle E. Morphometry of Left Frontal and Temporal Poles Predicts Analogical Reasoning Abilities. Cereb Cortex. 2014 Oct 19. pii: bhu254. 

Lagarde J, Valabrègue R, Corvol JC, Garcin B, Volle E, Le Ber I, Vidailhet M, Dubois B, Levy R. Why do patients with neurodegenerative frontal syndrome fail to answer: ‘In what way are an orange and a banana alike?’. Brain. 2015 Feb;138(Pt 2):456-71. doi: 10.1093/brain/awu359. 

Gil Gonen-Yaacovi Leonardo Cruz de Souza Richard Levy Marika Urbanski Goulven Josse Emmanuelle Volle. Rostral and caudal prefrontal contribution to creativity: A meta-analysis of functional imaging data. Front. Hum. Neurosci. Published on 14 Aug 2013, doi:10.3389/fnhum.2013.00465. 

Thiebaut de Schotten M., Dell’Acqua F., Forkel S.J., Simmons A., Vergani F., Murphy D.G.M., Catani M. (2011) A lateralized brain network for visuospatial attentionNat Neurosci 14:1245-1246.(IF 14.191).

Neuroimaging and behavior of the zebrafish

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

light-sheet microscopy
neuroimaging
zebrafish
sensory-motor integration
circuit inference

ENP label: 

2016

Research Center / Institute: 

Laboratoire Jean Perrin

Research Unit Code: 

UMR 8237

The overall objective of the group is to unravel principles of neural computations underlying sensory-motor integration in thevertebrate brain. We use the zebrafish larva as a model since it currently constitutes the only vertebrate system amenable towhole-brain recording with cellular resolution. Using one- or two-photon light-sheet microscopy, we are able to monitor the long-termactivity of the quasi-entirety of the 100,000 neurons that comprise the animal brain, as it performs basic sensory-motor tasks.

Leader

Leader: 

Personal

Team members: 

Raphaël Candelier
Sergei Kruglik
Sébastien Wolf
Alexis Dubreuil
Sophia Karpenko
Guillaume Le Goc
Institutions

Principal Institution: 

UPMC

Affiliated institutions: 

CNRS

University: 

Université Pierre et Marie Curie

Doctoral School: 

ED 564
Publications

Publications: 

Whole-brain functional imaging with two-photon light-sheet microscopy, S Wolf, W. Supatto, G. Debrégeas, P. Mahou, S. G Kruglik,J-M. Sintes, E. Beaurepaire, R. Candelier Nature Methods 12, 379–380 (2015)

An Amplitude Modulation/Demodulation Scheme for Whisker-Based Texture Perception, Y. Boubenec, L. N. Claverie, D. E. Shulz,G. Debrégeas, J. Neurosci. 34(33): 10832-10843 (2014)

Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy. T. Panier,S. Romano, R. Olive, T. Pietri, G. sumbre, R. Candelier, G. Debrégeas, Frontiers in Neural Circuits 7, 0065 (2013)

The role of fingerprints in the coding of tactile information probed with a biomimetic sensor, J. Scheibert, S. Leurent, A. Prevost et G. Debrégeas, Science 323 1503-1506 (2009). Reviewed in Science news, Science Update (radio), Science signaling, Nature news, Nature Research highlights, Nature Methods,Analytical Chemistry, Atten. Percept & Psych.

Signatures of granular microstructure in dense shear flows. D. Mueth, G. Debregeas, G. Karczmar, P. Eng, S. Nagel & H. Jaeger,Nature 406, 385-388 (2000)

Multisensory signal processing: From whole-brain activity to behavior

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

light-sheet microscopy
zebrafish
multisensory signal processing
whole-brain calcium imaging

ENP label: 

2016

Research Center / Institute: 

Laboratoire Jean Perrin

Research Unit Code: 

UMR 8237

Our brain needs to constantly fuse sensory information detected by our multiple senses in order to produce a seamless coherent representation of the world. Rather than being the exception, this binding process is ubiquitous to sensory-motor integration and is implicated in most cognitive functions. Its impairment is a cause of various pathologies, such as schizophrenia or autism. Multisensory processing operates on all brain levels from primary cortices over subcortical structures up to higher associative centers, while the smallest operational units are single multisensory neurons.

Leader

Leader: 

Personal

Team members: 

Thomas Panier (PostDoc)
Kris Severi (PostDoc)
Geoffrey Migault (PhD)
Hugo Trentenseaux (PhD)
Matthieu Dujany (Master)
Louis Chevalier (Master)
Institutions

Principal Institution: 

Sorbonne Université

Affiliated institutions: 

CNRS

University: 

UPMC

Doctoral School: 

ED 564
Laboratory

Surname: 

Bormuth
Publications

Publications: 

 Seclected Publications:

1. Migault G., van der Plas T.L.  , Trentesaux H. , Panier T., Candelier R., R. Proville , B. Englitz , Debrégeas G., Bormuth, V.  Whole-Brain Calcium Imaging during Physiological Vestibular Stimulation in Larval Zebrafish

Current Biology 28, 1-13 (2018)

2. Wolf S., Dubreuil A., Bertoni T., Böhm U.L., Bormuth V., Candelier R., Karpenko S., Hildebrand D.G.C. , Bianco I. H., Monasson R., Debrégeas G.     Sensorimotor computation underlying phototaxis in zebrafish.

Nature Communication 8, 651 (2017) 

3. Olive R., Wolf S., Dubreuil A., Bormuth V., Debregeas G., Candelier R.    Rheotaxis of Larval Zebrafish: Behavioral Study of a Multi-Sensory Process.

Frontiers in System Neuroscience 10, UNSP 14 (2016)

4. Bormuth, V., Barral, J., Joanny, J.F., Jülicher, F. & Martin, P.     Transduction channels gating controls friction on vibrating hair-cell bundles in the ear.

PNAS 111, 7185-90 (2014)

5. Gardner, M.K.*, Zanic, M.*, Gell, C., Bormuth, V., & Howard J.     Depolymerizing Kinesins Kip3 and MCAK Shape Cellular Microtubule Architecture by Differential Control of Catastrophe.

CELL 147, 1092-1103 (2011)  

6. Bormuth, V., Varga, V., Howard, J., & Schäffer, E.     Protein friction limits diffusive and directed movements of kinesin motors on microtubules.

SCIENCE 325, 870 - 873 (2009)  

7. Varga, V.*, Leduc, C.*, Bormuth, V., Diez, S., & Howard, J.     Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization.

CELL 138, 1174-83 (2009)  

8. Bormuth, V.*, Otsu, Y.*, et al.     Optical monitoring of neuronal activity at high frame rate with a digital random-access multiphoton (RAMP) microscope.

J. Neurosci. Methods 173(2), 259-270 (2008)    

Central COntrol oF Feeding behaviour and Energy Expenditure (C2OFFEE)

Main field of research: 

Neurophysiology / systems neuroscience

ENP label: 

2016

Research Center / Institute: 

Unité de Biologie Fonctionnelle et Adaptative BFA

Research Unit Code: 

UMR 8251

The modern abundance of energy-rich foods combined with a shift to more sedentary lifestyles has led to a thermodynamic imbalance, and consequently, excessive caloric intake and reduced energy expenditure are the main causes for the prevalence of obesity. According to the World Health Organization (WHO) the obesity worldwide obesity has more than doubled since 1980. In 2008, 1.5 billion adults, 20 and older, were overweight.

Leader

Leader: 

Personal

Team members: 

Julien Castel
Raphaël Denis
Claire Martin
Mar Quiñones Téllez
Anne-Sophie Delbes
Chloé Berland
Olja Kacanski
Institutions

Principal Institution: 

Université Paris Diderot

Affiliated institutions: 

CNRS

University: 

Université Paris Diderot

Doctoral School: 

ED157
Laboratory

Initiatives d'Excellence: 

USPC, collaborative ANR 2016
Publications

Publications: 

Garcia-Caceres, C., Quarta, C., Gao, Y., Varela, L., Gruber T, Legutko, B., Jastroch M., Johansson, P., Ninkovic J, Yi, CX., Le Thuc O, Meyer, C., Pfluger, PT., Fernandez AM., Luquet, S., Woods SC., Torres-Alemán, I., Kahn, C.R., Götz, M., Horvath, TL. & Tschöp, MH*. (2016) Astrocytic insulin signaling couples brain glucose uptake with nutrient availability. Cell 166, 867-880. (IF 2015:32.857)

 Denis, RG., Joly, A., Webber, E., Langlet, F., Schaeffer, M., Padilla, S., Cansell, C., Dehouck, B., Castel, J., Delbes, AS., Martinez, S.,Lacombe, A., Rouch, C., Kassis, N., Fehrentz,J-A., Martinez, J, Verdié, P., Hnasko, T, Palmiter, RD., Krashes, MJ., Güler, A., Magnan, C., Luquet, S (2015). Palatability can drive feeding independent of AgRP neurons. Cell Metab 22, 646-657. (IF 2015 :17.897)

Sun, X., Luquet, S., Small, DM. (2017). DRD2: Bridging the genome and ingestive behavior. Trends in Cognitive Sciences. Trends Cogn Sci 21, 372-384.. (IF 2015:17.85)

 Geurts, L., Everard, A., Van Hul, M., Essaghir, A., Duparc, T., Matamoros, S., Plovier, H., Castel, J., Denis, R.G., Bergiers, M., Druart, C., Alhouayek, M., Delzenne, N.M., Muccioli, G.G., Demoulin, J.B., Luquet, S., and Cani, P.D. (2015). Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nature communications 6, 6495 (IF2015: 12.00)

Cansell, C., Castel, J., Denis, R., Rouch, C., Delbes, AS., Martinez, S., Mestivier, D., Finan, B., Maldonado-Aviles, J.G, Rijnsburger, M.,  Tschöp, M.H., DiLeone, R.J., Eckel, R.H., La Fleur, S., Magnan, C., Hnasko, T., Luquet., S (2014). Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding. Mol Psychiatry 19, 1095-1105. (IF2015: 13.314)

Brain Dynamics

Main field of research: 

Cognitive neurosciences / neuropsychology /neuroeconomy

Keywords: 

Multisensory integration
magnetoencephalography
neural oscillations
temporal cognition

ENP label: 

2016

Research Center / Institute: 

Neurospin

Research Unit Code: 

U992

The Brain Dynamics group focuses on the chronoarchitecture of the Human brain supporting perception and cognition.Our work is committed to the view that perception and cognition rely on inferential brain processes which are fundamental to contemporary theories of cortical functions. Neural inferences are shaped by both hard and soft constraints e.g. cognitive architecture and plasticity, respectively.

Leader

Leader: 

Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

CEA
Direction des Sciences du Vivant
Institut d'Imagerie BioMédicale

Doctoral School: 

ED158 3C
Laboratory

Surname: 

Cognitive Neuroimaging Unit

Initiatives d'Excellence: 

IDEX Neuro Saclay
Publications

Publications: 

Gauthier B, van Wassenhove V. Time Is Not Space: Core Computations and Domain-Specific Networks for Mental Travels. J Neurosci. 2016 Nov 23;36(47):11891-11903. 

Martin, J. R., #Kösem, A., & #van Wassenhove, V. (2015). Hysteresis in Audiovisual Synchrony Perception. e0119365.

Strauss, M., Sitt, J. D., King, J. R., Elbaz, M., #Azizi, L., #Buiatti, M., ... & Dehaene, S. (2015). Disruption of hierarchical predictivecoding during sleep. Proceedings of the National Academy of Sciences, 112(11), E1353-E1362.

Strauss, M., Sitt, J., King, J. R., Elbaz, M., Azizi, L., #Buiatti, M., ... & Dehaene, S. (2015). Atteinte des processus de prédiction maisconservation de l’adaptation sensorielle au cours du sommeil. Médecine du Sommeil, 12(1), 58.

Strauss, M., Sitt, J., King, J. R., Elbaz, M., Naccache, L., #Van Wassenhove, V., & Dehaene, S. (2015). Atteinte des systèmesprédictifs dans le sommeil.Revue Neurologique, 171, A172.

#van Wassenhove, V., & #Grzeczkowski, L. (2015). Visual-induced expectations modulate auditory cortical responses. Frontiers inNeuroscience, 9, 11.

Spinal Physiology and Pathophysiology

Main field of research: 

Neurophysiology / systems neuroscience

Keywords: 

ALS
electrophysiology in vivo and in vitro
spinal cord circuitry
motoneuron
Renshaw cell

ENP label: 

2014

Research Center / Institute: 

INCC - UMR 8002 - Paris Descartes University

Research Unit Code: 

UMR8119

Our team investigates the relationships between spinal motoneurons and the muscle fibers they are targeting, and how thisrelationship is altered in the context of a human degenerative disease of motoneurons (ALS). To do so, we have recently pioneeredtwo new preparations that allow studying the electrophysiological properties of identified spinal motoneurons.

Leader

Leader: 

Institutions

Principal Institution: 

CNRS

Affiliated institutions: 

Université Paris Descartes

Doctoral School: 

ED3C
Laboratory

Surname: 

Centre de Neurophysique, Physiologie et Pathologie
Publications

Publications: 

Leroy F, Lamotte d'Incamps B, Zytnicki D. Potassium currents dynamically set the recruitment and firing properties of F-type motoneurons in neonatal mice. J Neurophysiol. 2015 Sep;114(3):1963-73. doi: 10.1152/jn.00193.2015. Epub 2015 Aug 12.

Leroy F#, Lamotte d'Incamps B#, Imhoff-Manuel RD#, Zytnicki D#. (2014) Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis. Elife Oct14;3. doi: 10.7554/eLife.04046.

Lamotte d’Incamps B#, Ascher P. (2014) High affinity and low affinity heteromeric nicotinic acetylcholine receptors at central synapses. J Physiol. Oct 1;592(Pt 19):4131-6

Delestrée N#, Manuel M#, Iglesias C, Elbasiouny SM, Heckman CJ, Zytnicki D#. (2014) Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis. J. Physiol. Apr 1;592(Pt 7):1687-703

Ritter LK, Tresch MC, Heckman CJ, Manuel M#, Tysseling VM. (2014) Characterization of motor units in behaving adult mice shows a wide primary range. J Neurophysiol. Aug 1;112(3):543-51

Manuel M#, Zytnicki D#, Meunier C. (2014) The dendritic location of the L-type current and its deactivation by the somatic AHP current both contribute to firing bistability in motoneurons. Front Comput Neurosci. Jan 27;8:4.

Biomarkers of relapse and therapeutic response in addictions and mood disorders

Main field of research: 

Neurological and psychiatric diseases

Keywords: 

addiction
Mood disorders
Neuropsychophamarcology
Genomics
Biomarkers

ENP label: 

2015

Research Center / Institute: 

UMR-S 1144 Therapeutic Optimisation in Neuropsychopharmacology

Research Unit Code: 

UMRS 1144

The "Biomarkers of relapse and therapeutic response in addictions and mood disorders" team develops research on mood disordersand addiction both at the clinical and fundamental level (ranked A, AERES 2013, creation 01/01/2014).The objective is to identifyclinical, biological, genetic or imaging-based markers of the response to psychotropic drugs (in the context of drug abuse or during thetreatment for mood disorders or pain management). These markers will allow us to better predict the response (therapeutic and sideeffects) in order to improve the therapeutic monitoring of patients.

Leader

Leader: 

Personal

Team members: 

Marie-Claire CYNTHIA
Jean-Louis LAPLANCHE
Jean-Pierre LEPINE
Emmanuel CURIS
Florence VORSPAN
Vanessa BLOCH
Frank QUESTEL
Sarah SPORTICHE
Gaël DUPUY
Institutions

Principal Institution: 

Inserm

Affiliated institutions: 

Université Paris Descartes
Université Paris Diderot

Doctoral School: 

ED 436
Laboratory

Surname: 

Variabilité de réponses aux psychotropes
Publications

Publications: 

Geoffroy PA# , Scott J, Boudebesse C, Lajnef M, Henry C, Leboyer M, Bellivier F# , Etain B. Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies. Acta Psychiatr Scand. 2014 28.

Bellivier F#, Geoffroy PA#, Etain B, Scott J. Sleep- and circadian rhythm-associated pathways as therapeutic targets in bipolar disorder. Expert Opin Ther Targets. 2015 Mar 2:1-17.

Boudebesse C, Geoffroy PA# , Henry C, Germain A, Scott J, Lajnef M, Leboyer M, Bellivier F# , Etain B. Eur Psychiatry. 2014 4.

Mouly S, Bloch V, Peoc'h K, Houze P, Labat L, Ksouda K, Simoneau G, Declèves X, Bergmann JF, Scherrmann JM, Laplanche JL#, Lepine JP#, Vorspan F#. Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity. Br J Clin Pharmacol. in press

Geoffroy PA# , Boudebesse C, Henrion A, Jamain S, Henry C, Leboyer M, Bellivier F# , Etain B. An ASMT variant associated with bipolar disorder influences sleep and circadian rhythms: a pilot study. Genes Brain Behav. 2014 13(3):299-304.

Development and Evolution of the Forebrain (DECA)

Main field of research: 

Neurogenetics / neurodevelopment

Keywords: 

Development, Evolution, Behavior, Adaptation, Evolutionary forces

ENP label: 

2015

Research Center / Institute: 

Institut des Neurosciences Paris-Saclay NeuroPSI

Research Unit Code: 

UMR9197

We address two questions:

1) Which mechanisms underly the evolution and the diversification of the vertebrate forebrain?

2) What are the evolutionary forces involved?

Leader

Leader: 

Institutions

Principal Institution: 

CNRS

Affiliated institutions: 

Université Paris Sud

University: 

Université Paris Sud

Doctoral School: 

ED 568 BioSigNe
Laboratory

Surname: 

Département Développement-Évolution

Initiatives d'Excellence: 

Idex NeuroSaclay
Publications

Publications: 

Hinaux H, Devos L, Blin M, Elipot Y, Bibliowicz J, Alié A, Rétaux S. Sensory evolution in blind cavefish is driven by early embryonic events during gastrulation and neurulation. Development. 2016 Dec 1;143(23):4521-4532. 

Yannick Elipot, Hélène Hinaux, Jacques Callebert, Jean-Marie Launay, Maryline Blin and Sylvie Rétaux (2014) A Mutation in theEnzyme Mono Amine Oxidase explains part of the Astyanax Cavefish Behavioural Syndrome. Nature Communications, 5:3647. IF10.

Yannick Elipot, Laurent Legendre, Stéphane Père, Frédéric Sohm and Sylvie Rétaux (2014) Astyanax transgenesis and husbandry:how cavefish enters the lab. Zebrafish, 11(4):291-9. IF3 (with cover picture)

Luis Espinasa, Jonathan Bibliowicz, William R. Jeffery, and Sylvie Rétaux. (2014) Enhanced prey capture skills in Astyanax cavefishlarvae are independent from eye loss. Evo Devo 5: 35.

Suzanne E. McGaugh, Joshua B. Gross, Bronwen Aken, Maryline Blin, Richard Borowsky, Domitille Chalopin, Hélène Hinaux, WilliamJeffery, Alex Keene, Li Ma, Pat Minx, Daniel Murphy, Kelly E. O’Quin, Sylvie Rétaux, Nicolas Rohner, Steve M. J. Searle, BethanyStahl, Cliff Tabin, Jean-Nicolas Volff, Masato Yoshizawa, Wes C. Warren. (2014) The cavefish genome reveals candidate genes foreye loss. Nature Communications, Oct 20; 5:5307.

Hélène Hinaux, Maryline Blin, Julien Fumey, Laurent Legendre, Didier Casane and Sylvie Rétaux (2014) Lens defects in Astyanaxmexicanus cavefish: focus on crystallin evolution and function. Developmental Neurobiology, 28. [Epub ahead of print].