Chloé Berland

Central COntrol oF Feeding behaviour and Energy Expenditure (C2OFFEE)

Main field of research: 

Neurophysiology / systems neuroscience

ENP label: 

2016

Research Center / Institute: 

Unité de Biologie Fonctionnelle et Adaptative BFA

Research Unit Code: 

UMR 8251

The modern abundance of energy-rich foods combined with a shift to more sedentary lifestyles has led to a thermodynamic imbalance, and consequently, excessive caloric intake and reduced energy expenditure are the main causes for the prevalence of obesity. According to the World Health Organization (WHO) the obesity worldwide obesity has more than doubled since 1980. In 2008, 1.5 billion adults, 20 and older, were overweight.

Leader

Leader: 

Personal

Team members: 

Julien Castel
Raphaël Denis
Claire Martin
Mar Quiñones Téllez
Anne-Sophie Delbes
Chloé Berland
Olja Kacanski
Institutions

Principal Institution: 

Université Paris Diderot

Affiliated institutions: 

CNRS

University: 

Université Paris Diderot

Doctoral School: 

ED157
Laboratory

Initiatives d'Excellence: 

USPC, collaborative ANR 2016
Publications

Publications: 

Garcia-Caceres, C., Quarta, C., Gao, Y., Varela, L., Gruber T, Legutko, B., Jastroch M., Johansson, P., Ninkovic J, Yi, CX., Le Thuc O, Meyer, C., Pfluger, PT., Fernandez AM., Luquet, S., Woods SC., Torres-Alemán, I., Kahn, C.R., Götz, M., Horvath, TL. & Tschöp, MH*. (2016) Astrocytic insulin signaling couples brain glucose uptake with nutrient availability. Cell 166, 867-880. (IF 2015:32.857)

 Denis, RG., Joly, A., Webber, E., Langlet, F., Schaeffer, M., Padilla, S., Cansell, C., Dehouck, B., Castel, J., Delbes, AS., Martinez, S.,Lacombe, A., Rouch, C., Kassis, N., Fehrentz,J-A., Martinez, J, Verdié, P., Hnasko, T, Palmiter, RD., Krashes, MJ., Güler, A., Magnan, C., Luquet, S (2015). Palatability can drive feeding independent of AgRP neurons. Cell Metab 22, 646-657. (IF 2015 :17.897)

Sun, X., Luquet, S., Small, DM. (2017). DRD2: Bridging the genome and ingestive behavior. Trends in Cognitive Sciences. Trends Cogn Sci 21, 372-384.. (IF 2015:17.85)

 Geurts, L., Everard, A., Van Hul, M., Essaghir, A., Duparc, T., Matamoros, S., Plovier, H., Castel, J., Denis, R.G., Bergiers, M., Druart, C., Alhouayek, M., Delzenne, N.M., Muccioli, G.G., Demoulin, J.B., Luquet, S., and Cani, P.D. (2015). Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nature communications 6, 6495 (IF2015: 12.00)

Cansell, C., Castel, J., Denis, R., Rouch, C., Delbes, AS., Martinez, S., Mestivier, D., Finan, B., Maldonado-Aviles, J.G, Rijnsburger, M.,  Tschöp, M.H., DiLeone, R.J., Eckel, R.H., La Fleur, S., Magnan, C., Hnasko, T., Luquet., S (2014). Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding. Mol Psychiatry 19, 1095-1105. (IF2015: 13.314)