RESEARCH HIGHLIGHT: TEMPORALLY PRECISE SINGLE-CELL-RESOLUTION OPTOGENETICS

Team leader Valentina Emiliani and coll in collaboration with Ed Boyden at MIT (Cambridge, USA) now devised a way to control single-neuron by optogenetics. Authors using a light-sensitive opsine protein targeted to neuronal bodies (soma-targeted) developed by Ed Boyden and taking advantage of the patterned 2-photon holographic illumination for optogenetics applications developed by the highly skilled expertise of the Emiliani’s team show exquisite figures and recordings of single synaptic response to stimulation paving therefore the way for a future clear neuronal connectivity map. READ MORE