École des Neurosciences Paris Île de France

Ana UZQUIANO

Program entrance date (month year): September 2014

Defense: 27 May 2019

Last update: 26-07-2018

Years 2-4

October 1, 2015 - September 30, 2019

Doctoral School Code: ED 515

University: Université Pierre et Marie Curie

Thesis title:

Progenitor cell mechanisms contributing to human brain malformations.

Thesis Supervisor: FRANCIS Fiona

Year 1

October 1, 2014 - September 30, 2015

UEI/Master: UEI (Unité d'Enseignement isolé)

University: Université Pierre et Marie Curie

Research project Title:

Lab rot 1:Adenosine signaling senses the activity of nascent synapses.

Lab rot 2: Analysis of demyelination and remyelination after optic nerve injury.

Lab rot 3: Progenitor cell mechanisms contributing to human brain malformations.

LabRotation 1: LEVI Sabine

LabRotation 2: CHEDOTAL Alain

LabRotation 3: FRANCIS Fiona

Biography/CV

PRIX : Dernière minute : juillet 2018

Grâce au soutien pérenne de la Fondation Valérie Chamaillard (sous l’égide de la Fondation de France), le prix « Valérie Chamaillard » de 30 K€ a été décerné à Ana UZQUIANO-LOPEZ doctorante ENP dans l’équipe dirigée par Fiona FRANCIS (Institut du Fer à Moulin, INSERM, Sorbonne Université) pour ses travaux de recherche réalisés sur l’épilepsie de l’enfant et/ou de l’adolescent.

PUBLICATIONS:

Montague K, Lowe AS, Uzquiano A, Knüfer A, Astick M, Price SR, Guthrie S.The assembly of developing motor neurons depends on an interplay between spontaneous activity, type II cadherins and gap junctions. Development. 2017 Mar 1;144(5):830-836. doi: 10.1242/dev.144063.

Team

Plasticity in Cortical Networks and Epilepsy

Leader: Jean Christophe PONCER

Co leader:

LEVI Sabine

Research theme: Cortical GABAergic interneurons play a critical role in shaping the activity of neuronal ensembles. In particular, in the hippocampus, GABA signaling is involved in the maintenance of rhythmic...

Cortical development and pathology

Leader: Fiona FRANCIS

Co leader:

GOUTEBROZE Laurence

Research theme: The group of F. Francis/L. Goutebroze focuses on three cortical development proteins mutated in malformations or more subtle cortical abnormalities. Cortical malformations are frequent causes of drug...